2010 Lexus RX MPG and Fuel Cost

The 2010 Lexus RX gets up to 21 mpg combined with a gas engine and up to 30 mpg as a hybrid, across 4 EPA-tested versions.

EPA fuel economy

2010 Lexus RX · 4 EPA-tested versions

Best gas version

21MPG combined

18 city 25 highway

$3,900 a year to fuel

3.5L 6-cyl · FWD · 6-speed automatic

Best hybrid version

30MPG combined

32 city 28 highway

$2,750 a year to fuel

3.5L 6-cyl hybrid · FWD · CVT

Best version costs $1,750 more in fuel over 5 years vs the average new vehicle (EPA)

Fuel cost: 15,000 miles a year at EPA's $5.48 a gallon (premium gas).

Data: US EPA, fueleconomy.govUpdated Oct 2, 2026

At EPA's price assumptions, fuel costs $2,750 to $4,100 a year.

One of the RX years to avoid

The 2010 drew 82 owner complaints in its first three years, against about 32 for a typical RX year: 2.6 times as many.

Years to avoid: 2010; best years: 2018, 2021, and 2022. Based on owner complaints, not adjusted for sales.

Every RX year ranked The 2010 RX's recalls and problems

Every 2010 RX version

EPA's ratings for each version it tested. Fuel cost is EPA's estimate for 15,000 miles a year at its current prices.

Version	Combined	City / Hwy	Fuel / year
Hybrid
3.5L 6-cyl hybrid · FWD · CVT Best EPA listing: RX 450h · Premium fuel	30 mpg	32 / 28	$2,750
3.5L 6-cyl hybrid · AWD · CVT EPA listing: RX 450h AWD · Premium fuel	29 mpg	30 / 28	$2,850
Gas
3.5L 6-cyl · FWD · 6-speed automatic EPA listing: RX 350 2WD · Premium fuel	21 mpg	18 / 25	$3,900
3.5L 6-cyl · AWD · 6-speed automatic EPA listing: RX 350 AWD · Premium fuel	20 mpg	18 / 24	$4,100

Fuel cost at your prices

EPA's annual cost uses 15,000 miles a year, 55% city driving and its current prices: $5.48 a gallon for premium gas. Change the numbers to match your driving.

Version	Per year	Per month	5 years
3.5L 6-cyl hybrid · FWD · CVT	$2,740	$228	$13,700
3.5L 6-cyl hybrid · AWD · CVT	$2,834	$236	$14,172
3.5L 6-cyl · FWD · 6-speed automatic	$3,914	$326	$19,571
3.5L 6-cyl · AWD · 6-speed automatic	$4,110	$342	$20,550

At the default settings the results match EPA's annual cost before EPA rounds it to the nearest $50.

Does the hybrid pay for itself? See the payback for every model sold both ways.

Lexus RX MPG by model year

The best-rated version in each model year; the highlighted year is this page. Gas: 21 to 25 mpg (every year from 2010 to 2026); 25 since 2023. Hybrid: 29 to 36 mpg (every year from 2010 to 2026); 36 since 2023.

Best gas version
Best hybrid version

2010: gas 21 mpg · hybrid 30 mpg

Show as a table

Lexus RX best combined mpg by model year
Model year	Best gas version	Best hybrid version
2010	21	30
2011	21	29
2012	21	29
2013	21	29
2014	21	29
2015	21	29
2016	23	30
2017	23	30
2018	23	30
2019	23	30
2020	23	30
2021	23	30
2022	23	30
2023	25	36
2024	25	36
2025	25	36
2026	25	36

Every RX year's ratings in one table

How the 2010 RX compares

2010 midsize SUVs covered on this site, ranked by their best combined rating. Fuel cost is for each model's cheapest version to run, at EPA's prices.

2010 model	Best combined	Best gas	Fuel / year
Lexus RX This page Best: hybrid	30 mpg	21 mpg	$2,750
Toyota Highlander Best: hybrid	26 mpg	22 mpg	$2,600
Hyundai Santa Fe Best: gas	23 mpg	23 mpg	$2,900
Ford Edge Best: gas	20 mpg	20 mpg	$3,350
Nissan Murano Best: gas	20 mpg	20 mpg	$4,100
Honda Pilot Best: gas	19 mpg	19 mpg	$3,550
Chevrolet Traverse Best: gas	19 mpg	19 mpg	$3,550
GMC Acadia Best: gas	19 mpg	19 mpg	$3,550
Buick Enclave Best: gas	19 mpg	19 mpg	$3,550
Jeep Grand Cherokee Best: gas	18 mpg	18 mpg	$3,700
Nissan Pathfinder Best: gas	18 mpg	18 mpg	$4,550
Mazda CX-9 Best: gas	18 mpg	18 mpg	$3,700
Ford Explorer Best: gas	17 mpg	17 mpg	$3,950

2010 RX recalls and complaints

NHTSA lists 1 safety recall and 192 owner complaints for the 2010 RX.

Owners most often describe unintended acceleration (30 complaints, 16%), then stalling (11).

See the 2010 RX recalls and problems

Questions

Does AWD lower the 2010 Lexus RX's gas mileage?

Yes. On versions that differ only in drive, AWD lowers the combined rating by 1 mpg: the 3.5L 6-cyl hybrid gets 30 mpg combined with front-wheel drive and 29 with AWD.

How much fuel does the 2010 RX hybrid save?

Comparing AWD or 4WD versions at EPA's assumptions (15,000 miles a year, $4.47 a gallon), the hybrid costs $2,850 a year to fuel against $4,100 for the gas model: $1,250 a year, or $6,250 over five years.

Does the 2010 Lexus RX need premium gas?

Yes. EPA lists the 3.5L 6-cyl versions and the 3.5L 6-cyl hybrid versions on premium.

Sources and method

US EPA and Department of Energy fuel economy data (fueleconomy.gov), file dated Sep 29, 2026.
EPA fuel price assumptions: regular $4.47, midgrade $5.07, premium $5.48, diesel $6.38 a gallon; electricity $0.15 per kWh.
Recall and complaint counts: NHTSA recall file dated Oct 2, 2026 and complaint file dated Oct 2, 2026.

Ratings are EPA estimates. Real-world mileage depends on how, where and in what weather you drive. How we build these pages. Spotted an error? Tell us.