2021 Toyota Sienna MPG and Fuel Cost
Every 2021 Toyota Sienna is a hybrid, rated 35 to 36 mpg combined across 2 versions.
EPA fuel economy
2021 Toyota Sienna · 2 EPA-tested versionsBest EPA rating
36MPG combined
36 city 36 highway
$1,800 a year to fuel
2.5L 4-cyl hybrid · FWD · CVT
Best version saves $2,500 in fuel over 5 years vs the average new vehicle (EPA)
Fuel cost: 15,000 miles a year at EPA's $4.32 a gallon (regular gas).
At EPA's price assumptions, fuel costs $1,800 to $1,850 a year. Every 2021 Sienna is a hybrid; the 2020 also came with gas engines.
Every 2021 Sienna version
EPA's ratings for each version it tested. Fuel cost is EPA's estimate for 15,000 miles a year at its current prices.
| Version | Combined | City / Hwy | Fuel / year |
|---|---|---|---|
2.5L 4-cyl hybrid · FWD · CVT Best
EPA listing: Sienna Hybrid 2WD |
36 mpg | 36 / 36 | $1,800 |
2.5L 4-cyl hybrid · AWD · CVT
EPA listing: Sienna Hybrid AWD |
35 mpg | 35 / 36 | $1,850 |
Fuel cost at your prices
EPA's annual cost uses 15,000 miles a year, 55% city driving and its current prices: $4.32 a gallon for regular gas. Change the numbers to match your driving.
| Version | Per year | 5 years |
|---|---|---|
2.5L 4-cyl hybrid · FWD · CVT | $1,800 | $9,000 |
2.5L 4-cyl hybrid · AWD · CVT | $1,851 | $9,257 |
At the default settings the results match EPA's annual cost before EPA rounds it to the nearest $50.
Toyota Sienna MPG by model year
The best-rated version in each model year; the highlighted year is this page. Gas: 21 to 22 mpg (2016 to 2020); highest in 2017. Hybrid: 36 mpg (2021 to 2026).
- Best gas version
- Best hybrid version
2021: gas not offered · hybrid 36 mpgTap or drag across the chart for other years.
Show as a table
| Model year | Best gas version | Best hybrid version |
|---|---|---|
| 2016 | 21 | – |
| 2017 | 22 | – |
| 2018 | 22 | – |
| 2019 | 22 | – |
| 2020 | 21 | – |
| 2021 | – | 36 |
| 2022 | – | 36 |
| 2023 | – | 36 |
| 2024 | – | 36 |
| 2025 | – | 36 |
| 2026 | – | 36 |
How the 2021 Sienna compares
2021 minivans covered on this site, ranked by their best combined rating. Fuel cost is for each model's cheapest version to run, at EPA's prices.
| 2021 model | Best combined | Best gas | Fuel / year |
|---|---|---|---|
Toyota Sienna This page Best: hybrid |
36 mpg | – | $1,800 |
Best: gas |
22 mpg | 22 mpg | $2,950 |
Best: gas |
22 mpg | 22 mpg | $2,950 |
2021 Sienna recalls and complaints
NHTSA lists 4 safety recalls and 208 owner complaints for the 2021 Sienna.What they cover, and crash test ratingsQuestions
Does AWD lower the 2021 Toyota Sienna's gas mileage?
Yes. On versions that differ only in drive, AWD lowers the combined rating by 1 mpg: the 2.5L 4-cyl hybrid gets 36 mpg combined with front-wheel drive and 35 with AWD.
Does the 2021 Toyota Sienna need premium gas?
No. EPA lists every 2021 Toyota Sienna version on regular gasoline.
Sources and method
- US EPA and Department of Energy fuel economy data (fueleconomy.gov), file dated Sep 18, 2026.
- EPA fuel price assumptions: regular $4.32, midgrade $4.93, premium $5.32, diesel $6.29 a gallon; electricity $0.15 per kWh.
- Recall and complaint counts: NHTSA recall file dated Sep 27, 2026 and complaint file dated Sep 26, 2026.
Ratings are EPA estimates. Real-world mileage depends on how, where and in what weather you drive. How we build these pages. Spotted an error? Tell us.